DRAWING ATTENTION TO A GLOBAL PANDEMIC - Diarrhoeal Disease

PREAMBLE: Diarrhoea remains the second leading cause of death among children under five globally, surpassed only by pneumonia, the most common cause. Nearly one in five child deaths – about 1.5 million each year – is due to diarrhoea. It kills more young children than AIDS, malaria and measles combined.

PacificSci wishes to draw attention to a recently released joint report from UNICEF and WHO that addresses this perennial global pandemic. Diarrhoeal disease, no longer a scourge in developed countries, attracts comparatively little attention from the international donor community, when compared with conditions such as HIV/AIDS, TB and malaria. And today, the media spotlight has shifted to H1N1 influenza, with little sense of proportionality in terms of continuing real disease burdens globally.

Acknowledgement: The material used in this edition of Global Perspectives is drawn almost verbatim from the Executive Summary of the joint UNICEF/WHO report, as referenced below.

THE REPORT:
In 2006, the United Nations Children’s Fund (UNICEF) and the World Health Organization (WHO) issued a report highlighting the most common cause of death among children (Pneumonia: The Forgotten Killer of Children). The purpose was to raise the profile of that neglected disease. This new report is written with the same intent – to focus attention on the prevention and management of diarrhoeal diseases as central to improving child survival. Together, pneumonia and diarrhoea are responsible for an estimated 40 per cent of all child deaths around the world each year.

There are lessons to be learned from past experience. An international commitment to tackle childhood diarrhoea in the 1970s and 1980s resulted in a major reduction in child deaths. This came about largely through the scaling up of oral rehydration therapy, coupled with programmes to educate caregivers on its appropriate use. But these efforts lost momentum as the world turned its attention to other global emergencies. Today, only 39 per cent of children with diarrhoea in developing countries receive the recommended treatment, and limited trend data suggest that there has been little progress since 2000.

This report examines the latest available information on the burden and distribution of childhood diarrhoea. It also analyses how well countries are doing in making available key interventions proven to reduce its toll. Most importantly, it lays out a new strategy for diarrhoea control, one that is based on interventions drawn from different sectors that have demonstrated potential to save children’s lives. It sets out a 7-point plan that includes a treatment package to reduce childhood diarrhoea deaths, as well as a prevention package to make a lasting reduction in the diarrhoea burden in the medium to long term.

New aspects of this approach include vaccinations for rotavirus, which is estimated to cause about 40 per cent of hospital admissions due to diarrhea among children under five worldwide.3 In terms of community-wide sanitation, new approaches to increase demand to stop open defecation have proven more effective than previous strategies. It has been estimated that 88 per cent of diarrhoeal deaths worldwide are attributable to unsafe water, inadequate sanitation and poor hygiene.

Actions needed to take interventions to scale
In many countries, progress has been made in the delivery or promotion of several of these interventions, particularly vitamin A supplementation and exclusive breastfeeding. However, a substantial reduction in the diarrhoea burden will require greater emphasis on the following actions:

■ Ensure wide availability of low-osmolarity ORS and zinc, which could have a profound impact on child deaths from diarrhoea if scaled up immediately. Possible strategies to increase their uptake and availability could include the development of smaller ORS packets and flavoured formulas, as well as delivering zinc and low-osmolarity ORS together in diarrhoea treatment kits.
■ Include rotavirus vaccine in national immunization programmes worldwide, which was recently recommended by the World Health Organization.

A 7-point plan for comprehensive diarrhoea control is outlined immediately below: two (#1 and #2) elements are contained with a treatment package”, while five (#3 to #7) are contained within a prevention package.

Treatment Package
The treatment package focuses on two main elements, as outlined in a 2004 joint statement from UNICEF and WHO: 1) fluid replacement to prevent dehydration and 2) zinc treatment. Oral rehydration therapy – which has been heralded as one of the most important medical advances of the 20th century – is the cornerstone of fluid replacement.

New aspects of this approach include low-osmolarity oral rehydration salts (ORS), which are more effective at replacing fluids than the original ORS formulation, and zinc treatment, which decreases diarrhea severity and duration. Important additional components of the package are continued feeding, including breastfeeding, during diarrhoea episodes and the use of appropriate fluids available in the home if ORS are not available, along with increased fluids in general.

Prevention Package
The prevention package highlights five main elements that require a concerted approach in their implementation. The package includes: 3) rotavirus and measles vaccinations, 4) promotion of early and exclusive breastfeeding and vitamin A supplementation, 5) promotion of handwashing with soap, 6) improved water supply quantity and quality, including treatment and safe storage of household water, and 7) community-wide sanitation promotion.

Key strategic elements include:■ Develop and implement behaviour change interventions, such as face-to-face counselling, to encourage exclusive breastfeeding.
■ Ensure sustained high levels of vitamin A supplementation, such as by combining its delivery, where effective, with other high-impact health and nutrition interventions.
■ Apply results of existing consumer research on how to motivate people to wash their hands with soap to increase this beneficial and cost-effective health practice. Handwashing with soap has been shown to reduce the incidence of diarrhoeal disease by over 40 per cent.
■ Adopt household water treatment and safe storage systems, such as chlorination and
filtration, in both development and emergency situations to support reductions in the number of diarrhoea cases.
■ Implement approaches that increase demand to stop community-wide open defecation. As with handwashing, the new approach employs behavioural triggers, such as pride, shame and disgust, to motivate action, and leads to greater ownership and sustainability of programmes.

The report states: “We know what works to immediately reduce deaths from childhood diarrhoea. We also know what actions will make a lasting contribution to reducing the toll of diarrhoeal diseases for years to come. But strengthened efforts on both fronts must begin right away.”

The following actions are needed to take the 7-point plan to scale:
■ Mobilize and allocate resources for diarrhea control.
■ Reinstate diarrhoea prevention and treatment as a cornerstone of community-based primary health care.
■ Ensure that low-osmolarity ORS and zinc are adopted as policy in all countries.
■ Reach every child with effective interventions.
■ Accelerate the provision of basic water and sanitation services.
■ Use innovative strategies to increase the adoption of proven measures against diarrhoea.
■ Change behaviours through community involvement, education and health-promotion activities.
■ Make health systems work to control diarrhoea.
■ Monitor progress at all levels, and make the results count.
■ Make the prevention and treatment of diarrhea everybody’s business.

The Executive Summary to the report concludes with the statement that "There is no better time than now. Political momentum is building to address the leading causes of child deaths, including pneumonia and diarrhoea, to achieve measurable gains in child survival. The year 2008 marked the 30th anniversary of the Alma- Ata Declaration, with reinvigorated calls to focus on primary health care. Lessening the burden of childhood diarrhoea fits squarely with this emphasis, and is essential for achieving Millennium Development Goal 4: reduce child mortality, whose target date is now only six years away."

SOURCE: Executive Summary. Diarrhoea :Why children are still dying and what can be done. The United Nations Children’s Fund (UNICEF)/World Health Organization (WHO), 2009. http://whqlibdoc.who.int/publications/2009/9789241598415_eng.pdf

OFFICIAL DEVELOPMENT ASSISTANCE AND GLOBAL HEALTH TRENDS

PREAMBLE: During our first 6 months, this report addressed the following global issues: climate change, child development, colonized minorities, food security, human rights, and other news and reviews. In most instances we also addressed the relevance of these issues to Canada, our home base. To locate these issues you may either scan down this issue to earlier issues, or Google search by combining the keywords just noted with the term pacificsci.

This June 2007 issue reviews the vexing issue of official development assistance from wealthy developed countries such as Canada, makes reference to a report on global social and economic trends, then selects reports from a discipline that is essential to understanding global health trends: Health Situation Analysis. This refers to information on health conditions, supported by vital and health statistics critical to strategic and operational development planning. Our selected examples include Africa, the State of the World Children, and Projections of Mortality and Burden of Disease to 2030.

Our sidebar addresses the emergence of “corporate hybrids”, freedom of speech and tolerance for intellectual opinions.

 G7 OFFICIAL DEVELOPMENT ASSISTANCE (ODA)
The most recent confirmed OECD data for ODA (2005) reveal that, although absolute amounts are higher, G7 countries allocate proportionally less Gross National Income (GNI) for international development: 0.30%, compared with .50% for non-G7 nations. Of 22 OECD nations only 5 met the UN target of at least 0.7%: Norway, Sweden, Denmark, the Netherlands, and Luxembourg, none of which are G7 countries. The lowest G7 allocation is made by the USA (0.22%; among 15 non- G7 nations, only Portugal and Greece give less than this), while Canada comes in slightly above the G7 mean at 0.34%. Clearly, both individually and collectively, the G7 should show more leadership.

Note: OECD rankings do not include Russia, a G8 country (G7 + 1).
Reference: Final ODA Data for 2005. http://www.oecd.org/dataoecd/52/18/37790990.pdf

 SERIOUS QUESTIONS ABOUT CANADA’s ODA
Questions are being raised about Canada’s ODA priorities eg., $30 million in 2006 to China, an emerging political and economic powerhouse. Parliamentarians urging increased aid to truly poor nations say the government’s refusal to support proposed new legislation to guide ODA reveals lack of commitment. “Canada used to be a leader and is now a… laggard” said Alexa McDonough, NDP foreign affairs critic. According to McDonough, the planned 2006 ODA of just over $3 billion represents 0.32 % of GNI, down from 0.34% last year and far off the 0.7% target that Canada helped set. Josee Verner, Minister for international aid, replied “spending in 2007-08 will increase by 8%, in line with the goal of doubling by 2011 the amount spent on ODA in 2001”.
Source: Sue Bailey. The Canadian Press. March 27, 2007
EDITORIAL: an annual increase in absolute expenditures in the order of 8% will simply maintain the status quo with little movement towards the target of 0.7% GNI

 REPORT FROM 8TH GLOBAL DEVELOPMENT CONFERENCE, Beijing. For up-to-date social and economic trends, visit the Global Development Network April 2007 newsletter. Topics include: the rise of Asia in the global economy; growth and poverty in Latin America; structural transformation opportunities in Africa and the Middle East. http://www.gdnet.org/pdf2/research_monitor/2007-April_conference%20edition_Research%20Monitor.pdf

 HEALTH SITUATION OF SUB-SAHARAN AFRICA

The health situation of Sub-Saharan Africa (SSA) is the least favourable of all regions. Following steady declines until the mid-1990s, adult mortality sharply reversed, with the disease burden increasingly dominated by HIV/AIDS superimposed on already heavy burdens from endemic malaria, water-borne diseases, vaccine-preventable diseases, nutritional deficiencies, and other preventable conditions. In some settings, this was compounded by war and civil strife, with consequent increases in violent death, food shortages, poverty and displacement of people, further fueling a rural to urban migration for economic survival. In parts of SSA, adult mortality rates are at their highest in 3 decades; a rapid drop in life expectancy (LE) is seen in 38 countries (LE age 40 or less in 8 of these). Without HIV/AIDS, LE at birth would have been almost 6.1 years higher in 2002. The slippage is not only due to HIV/AIDS: for example, despite major gains in immunization coverage during the 1980s, these have reversed since, reflecting a loss of capacity to deliver primary health care. In the meantime, the health profiles of Africa and the world are not standing still: the pattern is shifting with a steady increase in Non-Communicable Diseases and injuries. Even given Africa’s preoccupation with infectious diseases, which still dominate the disease burden, planners must now be alert to this emerging and future disease burden.
Source: The foregoing brief report is a paraphrased extract from a health situation analysis carried out by PacificSci for an assignment in East Africa completed in 2006.

 THE HEALTH OF THE PEOPLE: THE AFRICAN REGIONAL HEALTH REPORT: A fully comprehensive situation analysis has recently been published by the WHO Regional Office for Africa. http://www.who.int/bulletin/africanhealth/en/index.html

 THE STATE OF THE WORLD’s CHILDREN 2007

This UNICEF report focuses on the discrimination and disempowerment experienced by women and girls. It discusses how gender equality will move the UN Millennium Development Goals forward, and how investment in women’s rights will ultimately produce a dual dividend: advancing the rights of women and children. Seven interventions are advocated:

1. Abolish school fees and invest in girls' education
2. Invest government funding in gender equality
3. Enact legislation to create a level playing field for women and to address domestic as well as gender-based violence
4. Ensure women's participation in politics
5. Involve women's grassroots organizations in policy development
6. Engage men and boys on the importance of gender equality
7. Improve research and data on gender issues.
For the full report as a PDF document: http://www.unicef.org/sowc07/report/report.php

 PROJECTIONS OF MORTALITY & DISEASE BURDEN TO 2030

Revised global and regional projections of mortality and burden of disease by cause for 2005, 2015 and 2030 are now available from the World Health Organization. Principal investigators (CD Mathers & D Loncar) applied separate projection models for males and females, stratified into 7 age groups. The website below offers online access to the article, a working paper, and references to papers on data sources and methods. Detailed results for projected deaths and DALYs can be downloaded as Excel spreadsheets. The analyses were carried out at country level with aggregation into regional or income groups. The investigators used socio-economic projections to model future mortality and morbidity patterns, assuming slower and faster rates of development and population growth, taking into account independent variables: income, education, time, and tobacco use. The results suggest that, from 2002 to 2030, life expectancy will increase throughout the world, with an upward shift in the age of deaths, with considerably fewer younger children dying, while deaths due to cancer and heart disease will increase. Deaths from infectious diseases will decline overall, while mortality from HIV/AIDS will continue to increase. http://www.who.int/healthinfo/statistics/bodprojections2030/en/index.html

Acknowledgment: In constructing our summary, a review by Robert Goldberg on ProCOR (Recommended link in sidebar) was helpful, including his note of caution regarding the quality of data used to develop the predictive models and assumptions utilized.

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